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1

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

Li-Rung Chen, Yu-Chin Wang, Yi Wen Lin, Shan-Yen Chou, Shyh-Fong Chen, Lee Tai Liu, Ying-Ta Wu, Chih-Jung Kuo, Tom Shieh-Shung Chen, Shin-Hun Juang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 576 KB

english, 2005

2

ChemInform Abstract: A Stereoselective Synthesis of (E)-1-Halo-6,6-dimethyl-2-hepten-4-yne: A Key Intermediate for Terbinafine.

Shan-Yen Chou, Chin-Lu Tseng, Shyh-Fong Chen

Journal:

Year:

2000

File:

PDF, 30 KB

2000

3

A new inhibitor for fructosamine 3-kinase (Amadorase)

Henry J. Tsai, Shan-Yen Chou, Frank Kappler, Michael L. Schwartz, Annette M. Tobia

Journal:

Drug Development Research

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

4

D-420720, A novel orally active sulfonamide compound dipeptidyl peptidase IV inhibitor: structure and activity relationship of arylsulfonamide to dipeptidyl peptidase IV inhibition

Henry J. Tsai, Shan-Yen Chou, Shih-Hsien Chuang, Chien-Cheng Chen, Feng-Lin Hsu

Journal:

Drug Development Research

Year:

2008

Language:

english

File:

PDF, 99 KB

english, 2008

5

Regioselective synthesis of 3-(1H-indol-3-yl)-5-(1H-indole-3-carbonyl)-4-hydroxyfuroic acids: route to hydroxyfuroic acid-based insulin receptor activators

Shan-Yen Chou, Henry J. Tsai

Journal:

Drug Development Research

Year:

2011

Language:

english

File:

PDF, 172 KB

english, 2011

6

Linker-modified triamine-linked acridine dimers: Synthesis and cytotoxicity properties in vitro and in vivo

Shan-Shue Wang, Yi-Jen Lee, Shih-Chung Hsu, Hsueh-O Chang, Wei-Kung Yin, Lien-Shange Chang, Shan-Yen Chou

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 298 KB

english, 2007

7

Base-mediated hydrolytic cleavage with chain migration of 1-chloromethyl-tetrahydropyrano[3,4-b]indoles: an unusual pathway to 2-succinoyl tryptophols

Shan-Yen Chou, Ching-Hui Chen

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 118 KB

english, 2006

8

Regioselective synthesis of 3-aryl-5-(1H-indole-3-carbonyl)-4-hydroxyfuroic acids as potential insulin receptor activators

Shan-Yen Chou, Shieh-Shung Tom Chen, Ching-Hui Chen, Lien-Shange Chang

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

9

A stereoselective synthesis of (E)-1-halo-6,6-dimethyl-2-hepten-4-yne: a key intermediate for terbinafine

Shan-Yen Chou, Chin-Lu Tseng, Shyh-Fong Chen

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

10

Corrigendum to “A stereoselective synthesis of (E)-1-halo-6,6-dimethyl-2-hepten-4-yne: a key intermediate for terbinafine”: [Tetrahedron Letters 41 (2000) 3895]

Shan-Yen Chou, Chin-Lu Tseng, Shyh-Fong Chen

Journal:

Tetrahedron Letters

Year:

2000

File:

PDF, 27 KB

2000

11

A novel hydroxyfuroic acid compound as an insulin receptor activator - structure and activity relationship of a prenylindole moiety to insulin receptor activation

Henry J Tsai, Shan-Yen Chou

Journal:

Journal of Biomedical Science

Year:

2009

Language:

english

File:

PDF, 665 KB

english, 2009

12

Increasing antitumor activity in vivo by enhancing acridine dimer solubility with salt preparations

Shan-Shue Wang, Yi-Jen Lee, Shih-Chung Hsu, Chen Hsieh, Lien-Shange Chang, Shan-Yen Chou

Journal:

Medicinal Chemistry Research

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

13

The mechanism investigation in substitution of 21-bromo-3α-hydroxyl-3β-methoxymethyl-5α-pregnan-20-one with nucleophiles

Chun-Yen Chen, Fung Fuh Wong, Yueh-Hsien Lee, Shan-Yen Chou, Jiann-Jyh Huang, Mou-Yung Yeh

Journal:

Year:

2006

Language:

english

File:

PDF, 463 KB

english, 2006

14

Kilogram-Scale Synthesis of a Highly Selective α 1 -Adrenoceptor Antagonist (DL-028A)

Chou, Shan-Yen, Yin, Wei-Kung, Chung, Yuh-Shan, Chang, Lien-Shange, Liu, Chin-Wei, Chen, Shyh-Fong, Shih, Kae-Shyang

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

15

Preparation of 3,4,5,3′-Tetramethoxy-4′,5′-Methylenedioxybenzophenone and Bis-(3-Methoxy-4,5-Methylenedioxy)-Benzophenone

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1990

Language:

english

File:

PDF, 552 KB

english, 1990

16

Synthesis of 2-Hydroxymethyl-3,5-dimethyl-4-methoxypyridine : A Key Intermediate for Omeprazole

Chou, Shan-Yen, Chen, Shyh-Fong

Journal:

Year:

1997

Language:

english

File:

PDF, 218 KB

english, 1997

17

An Anomalous Preparing of a Tetrahydro-2H-oxocine Fused Pyrrole Derivative and Its Acid-catalyzed Rearrangement

Chou, Shan-Yen, Chang, Lien-Shange, Chen, Shyh-Fong

Journal:

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

18

Fragmentation of α-Acetoximino Ketoesters in Polyphosphoric Acid

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1994

Language:

english

File:

PDF, 666 KB

english, 1994

19

An Acid-Catalyzed Fragmentation Reaction of a Triamine-Linked Acridine Dimer

Chou, Shan-Yen, Yin, Wei-Kung

Journal:

Journal of the Chinese Chemical Society

Year:

2001

Language:

english

File:

PDF, 42 KB

english, 2001

20

Stereoselective Synthesis of (+)-Peperomin C

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1991

Language:

english

File:

PDF, 583 KB

english, 1991

21

A Novel Substitution Reaction of Tetrahydropyrano[3,4-b]indole Derivative — Chain Extension and Structural Correlation Study

Journal:

Year:

2003

Language:

english

File:

PDF, 742 KB

english, 2003

22

Synthesis of (±) Peperomins

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1990

Language:

english

File:

PDF, 431 KB

english, 1990

23

The Synthesis of (±)-α-Vetispirene Via the Dieckmann Condensation of Ethyl 4-(2,6-Dimethyl-1-Carbethoxycyclohex-2-Enyl)-Butyrate

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1988

Language:

english

File:

PDF, 240 KB

english, 1988

24

Synthesis of (±)-Lsodeoxypodophyllotoxin

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1992

Language:

english

File:

PDF, 290 KB

english, 1992

25

Exploration of an Efficient Method for Optical Resolution of Etodolac

Chou, Shan-Yen, Tseng, Chin-Lu, Chang, Lien-Shange

Journal:

Journal of the Chinese Chemical Society

Year:

2001

File:

PDF, 315 KB

2001

26

An Efficient Synthesis of (±)-α-Spirovetivene and Related Compounds

Zee, Sheng-Hsu, Chou, Shan-Yen

Journal:

Journal of the Chinese Chemical Society

Year:

1990

Language:

english

File:

PDF, 515 KB

english, 1990

27

The Syntheses of Triazole, Sulfur-Containing Diazole and n -Phenylthiatriazole Biphenyltetrazoles as Potential Angiotensin II Receptor Antagonists

Chou, Shan-Yen, Chen, Sn-San, Ho, Chin-Chung, Huang, Shiang-Ling, Huang, Tsai-Mien, Pan, Ohm-Guo, Wang, Chia-Lin, Chen, Ying, Lu, Hsiao-Hwa, Liu, Shih-Hwa, Huang, Shir-Ly, Chiang, Ren-Shou

Journal:

Journal of the Chinese Chemical Society

Year:

1996

Language:

english

File:

PDF, 876 KB

english, 1996